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JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma

Chemotherapy resistance poses an obstacle for effective treatment of uveal melanoma. In this study, we aim to investigate the effects of jumonji domain containing 2C (JMJD2C)-mediated mouse double minute-2 homolog (MDM2)/p53/interleukin 5 receptor subunit alpha (IL5RA) axis on cisplatin (CDDP) resis...

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Detalles Bibliográficos
Autores principales: Zhu, Qi, Chen, Han, Li, Xiaoying, Wang, Xi, Yan, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039082/
https://www.ncbi.nlm.nih.gov/pubmed/35468881
http://dx.doi.org/10.1038/s41420-022-00949-y