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JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma
Chemotherapy resistance poses an obstacle for effective treatment of uveal melanoma. In this study, we aim to investigate the effects of jumonji domain containing 2C (JMJD2C)-mediated mouse double minute-2 homolog (MDM2)/p53/interleukin 5 receptor subunit alpha (IL5RA) axis on cisplatin (CDDP) resis...
Autores principales: | Zhu, Qi, Chen, Han, Li, Xiaoying, Wang, Xi, Yan, Hongtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039082/ https://www.ncbi.nlm.nih.gov/pubmed/35468881 http://dx.doi.org/10.1038/s41420-022-00949-y |
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