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The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells

Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by reduced differentiation of myeloid cells and uncontrolled cell proliferation. AML is prone to drug resistance and has a high recurrence rate during treatment with cytarabine-based chemotherapy. Our study aims to...

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Detalles Bibliográficos
Autores principales: Ma, Xiangyu, Zhao, Mengjie, Wu, Zhuo-Xun, Yao, Jingfang, Zhang, Lei, Wang, Jinhong, Hu, Zhenbo, Wei, Liuya, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039182/
https://www.ncbi.nlm.nih.gov/pubmed/35494054
http://dx.doi.org/10.3389/fonc.2022.855570