Camptothecin Delivery via Tumor-Derived Exosome for Radiosensitization by Cell Cycle Regulation on Patient-Derived Xenograft Mice

Purpose: While radiotherapy remains the leading clinical treatment for many tumors, its efficacy can be significantly hampered by the insensitivity of cells in the S phase of the cell cycle to such irradiation. Methods: Here, we designed a highly targeted drug delivery platform in which exosomes wer...

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Detalles Bibliográficos
Autores principales: Yang, Yiling, Ren, Shiqi, Huang, Wenpeng, Dong, Jiahan, Guo, Jiancheng, Zhao, Jie, Zhang, Yonggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039187/
https://www.ncbi.nlm.nih.gov/pubmed/35497339
http://dx.doi.org/10.3389/fbioe.2022.876641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039187/
https://www.ncbi.nlm.nih.gov/pubmed/35497339
http://dx.doi.org/10.3389/fbioe.2022.876641

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