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Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis

The 2013–2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV glycoprotein (GP) are strongly associated with survival and their use in immunotherapy is often initially based on their perform...

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Detalles Bibliográficos
Autores principales: Mellors, Jack, Tipton, Tom, Fehling, Sarah Katharina, Akoi Bore, Joseph, Koundouno, Fara Raymond, Hall, Yper, Hudson, Jacob, Alexander, Frances, Longet, Stephanie, Taylor, Stephen, Gorringe, Andrew, Magassouba, N’Faly, Konde, Mandy Kader, Hiscox, Julian, Strecker, Thomas, Carroll, Miles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039621/
https://www.ncbi.nlm.nih.gov/pubmed/35493467
http://dx.doi.org/10.3389/fimmu.2022.857481