Cargando…

Srebf1c preserves hematopoietic stem cell function and survival as a switch of mitochondrial metabolism

Mitochondria are fundamental but complex determinants for hematopoietic stem cell (HSC) maintenance. However, the factors involved in the regulation of mitochondrial metabolism in HSCs and the underlying mechanisms have not been fully elucidated. Here, we identify sterol regulatory element binding f...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yukai, Zhang, Zihao, Wang, Song, Qi, Yan, Chen, Fang, Xu, Yang, Shen, Mingqiang, Chen, Mo, Chen, Naicheng, Yang, Lijing, Chen, Shilei, Wang, Fengchao, Su, Yongping, Hu, Mengjia, Wang, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039836/
https://www.ncbi.nlm.nih.gov/pubmed/35148846
http://dx.doi.org/10.1016/j.stemcr.2022.01.011