Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis

OBJECTIVE: Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG-CoA synthase deficiency) is commonly associated with the development of the fatty liver. Here we aimed to determine...

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Detalles Bibliográficos
Autores principales: Asif, Shaza, Kim, Ri Youn, Fatica, Thet, Sim, Jordan, Zhao, Xiaoling, Oh, Yena, Denoncourt, Alix, Cheung, Angela C., Downey, Michael, Mulvihill, Erin E., Kim, Kyoung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039870/
https://www.ncbi.nlm.nih.gov/pubmed/35421611
http://dx.doi.org/10.1016/j.molmet.2022.101494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039870/
https://www.ncbi.nlm.nih.gov/pubmed/35421611
http://dx.doi.org/10.1016/j.molmet.2022.101494

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