Cargando…

RePhine: An Integrative Method for Identification of Drug Response-related Transcriptional Regulators

Transcriptional regulators (TRs) participate in essential processes in cancer pathogenesis and are critical therapeutic targets. Identification of drug response-related TRs from cell line-based compound screening data is often challenging due to low mRNA abundance of TRs, protein modifications, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xujun, Zhang, Zhengtao, Qin, Wenyi, Liu, Shiyi, Liu, Cong, Genchev, Georgi Z., Hui, Lijian, Zhao, Hongyu, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040019/
https://www.ncbi.nlm.nih.gov/pubmed/33713851
http://dx.doi.org/10.1016/j.gpb.2019.09.008