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RePhine: An Integrative Method for Identification of Drug Response-related Transcriptional Regulators
Transcriptional regulators (TRs) participate in essential processes in cancer pathogenesis and are critical therapeutic targets. Identification of drug response-related TRs from cell line-based compound screening data is often challenging due to low mRNA abundance of TRs, protein modifications, and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040019/ https://www.ncbi.nlm.nih.gov/pubmed/33713851 http://dx.doi.org/10.1016/j.gpb.2019.09.008 |