High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Genome engineering of T lymphocytes, the main effectors of antitumor adaptive immune responses, has the potential to uncover unique insights into their functions and enable the development of next-generation adoptive T cell therapies. Viral gene delivery into T cells, which is currently used to gene...

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Detalles Bibliográficos
Autores principales: Oh, Soyoung A., Senger, Kate, Madireddi, Shravan, Akhmetzyanova, Ilseyar, Ishizuka, Isabel E., Tarighat, Somayeh, Lo, Jerry H., Shaw, David, Haley, Benjamin, Rutz, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Technical Advances and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040063/
https://www.ncbi.nlm.nih.gov/pubmed/35452075
http://dx.doi.org/10.1084/jem.20211530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040063/
https://www.ncbi.nlm.nih.gov/pubmed/35452075
http://dx.doi.org/10.1084/jem.20211530

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