Cargando…
High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA
Genome engineering of T lymphocytes, the main effectors of antitumor adaptive immune responses, has the potential to uncover unique insights into their functions and enable the development of next-generation adoptive T cell therapies. Viral gene delivery into T cells, which is currently used to gene...
Autores principales: | Oh, Soyoung A., Senger, Kate, Madireddi, Shravan, Akhmetzyanova, Ilseyar, Ishizuka, Isabel E., Tarighat, Somayeh, Lo, Jerry H., Shaw, David, Haley, Benjamin, Rutz, Sascha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040063/ https://www.ncbi.nlm.nih.gov/pubmed/35452075 http://dx.doi.org/10.1084/jem.20211530 |
Ejemplares similares
-
Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9
por: Sun, Yonghua, et al.
Publicado: (2020) -
Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing
por: Sinclair, Frazer, et al.
Publicado: (2023) -
Computational Tools and Resources for CRISPR/Cas Genome Editing
por: Li, Chao, et al.
Publicado: (2023) -
Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
por: Freund, Emily C., et al.
Publicado: (2020) -
Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children
por: Altman, Matthew C., et al.
Publicado: (2019)