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Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8

MARCH1 and MARCH8 are ubiquitin ligases that control the expression and trafficking of critical immunoreceptors. Understanding of their function is hampered by three major knowledge gaps: (i) it is unclear which cell types utilize these ligases; (ii) their level of redundancy is unknown; and (iii) m...

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Detalles Bibliográficos
Autores principales: Schriek, Patrick, Liu, Haiyin, Ching, Alan C., Huang, Pauline, Gupta, Nishma, Wilson, Kayla R., Tsai, MinHsuang, Yan, Yuting, Macri, Christophe F., Dagley, Laura F., Infusini, Giuseppe, Webb, Andrew I., McWilliam, Hamish E.G., Ishido, Satoshi, Mintern, Justine D., Villadangos, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040089/
https://www.ncbi.nlm.nih.gov/pubmed/35492398
http://dx.doi.org/10.1016/j.crimmu.2021.10.004