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Heterologous vaccine therapy associated with half course of Miltefosine promote activation of the proinflammatory response with control of splenic parasitism in a hamster model of visceral leishmaniasis

Visceral leishmaniasis (VL) is a serious and neglected disease present worldwide. Chemotherapy using pentavalent antimony (Sb(V)) is the most practical and inexpensive strategy available for the VL treatment today, however, it has high toxicity. Alternatively, other drugs are used as viable leishman...

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Detalles Bibliográficos
Autores principales: Carvalho, Lívia Mendes, Ferreira, Francielle Carvalho, Gusmão, Miriã Rodrigues, Costa, Ana Flávia Pereira, de Brito, Rory Cristiane Fortes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Alexandre Barbosa, Cardoso, Jamille Mirelle de Oliveira, Carneiro, Cláudia Martins, Roatt, Bruno Mendes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040144/
https://www.ncbi.nlm.nih.gov/pubmed/35492387
http://dx.doi.org/10.1016/j.crimmu.2021.10.003