Impact of IgG1 N-glycosylation on their interaction with Fc gamma receptors

The effector functions of the IgGs are modulated by the N-glycosylation of their Fc region. Particularly, the absence of core fucosylation is known to increase the affinity of IgG1s for the Fcγ receptor IIIa expressed by immune cells, in turn translating in an improvement in the antibody-dependent c...

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Detalles Bibliográficos
Autores principales: Cambay, Florian, Raymond, Céline, Brochu, Denis, Gilbert, Michel, Tu, The Minh, Cantin, Christiane, Lenferink, Anne, Grail, Maxime, Henry, Olivier, De Crescenzo, Gregory, Durocher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040152/
https://www.ncbi.nlm.nih.gov/pubmed/35493857
http://dx.doi.org/10.1016/j.crimmu.2020.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040152/
https://www.ncbi.nlm.nih.gov/pubmed/35493857
http://dx.doi.org/10.1016/j.crimmu.2020.06.001

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