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Promoting antigen escape from dendritic cell endosomes potentiates anti-tumoral immunity

The cross-presenting capacity of dendritic cells (DCs) can be limited by non-specific degradation during endosome maturation. To bypass this limitation, we present in this study a new Accum-based formulation designed to promote endosome-to-cytosol escape. Treatment of primary DCs with Accum linked t...

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Detalles Bibliográficos
Autores principales: Bikorimana, Jean-Pierre, Salame, Natasha, Beaudoin, Simon, Balood, Mohammad, Crosson, Théo, Abusarah, Jamilah, Talbot, Sebastien, Löbenberg, Raimar, Plouffe, Sebastien, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040180/
https://www.ncbi.nlm.nih.gov/pubmed/35492876
http://dx.doi.org/10.1016/j.xcrm.2022.100534