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Harnessing the chemokine system to home CAR-T cells into solid tumors

CAR-T cell therapy has been heralded as a breakthrough in the field of immunotherapy, but to date, this success has been limited to hematological malignancies. By harnessing the chemokine system and taking into consideration the chemokine expression profile in the tumor microenvironment, CAR-T cells...

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Detalles Bibliográficos
Autores principales: Foeng, Jade, Comerford, Iain, McColl, Shaun R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040186/
https://www.ncbi.nlm.nih.gov/pubmed/35492880
http://dx.doi.org/10.1016/j.xcrm.2022.100543