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Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer

Prostate cancer continuously progresses following deprivation of circulating androgens originating from the testis and adrenal glands, indicating the existence of oncometabolites beyond androgens. In this study, mass-spectrometry-based screening of clinical specimens and a retrospective analysis on...

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Detalles Bibliográficos
Autores principales: Hou, Zemin, Huang, Shengsong, Mei, Zejie, Chen, Longlong, Guo, Jiacheng, Gao, Yuanyuan, Zhuang, Qian, Zhang, Xuebin, Tan, Qilong, Yang, Tao, Liu, Ying, Chi, Yongnan, Qi, Lifengrong, Jiang, Ting, Shao, Xuefeng, Wu, Yan, Xu, Xiaojun, Qin, Jun, Ren, Ruobing, Tang, Huiru, Wu, Denglong, Li, Zhenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040187/
https://www.ncbi.nlm.nih.gov/pubmed/35492874
http://dx.doi.org/10.1016/j.xcrm.2022.100561