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Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer
Prostate cancer continuously progresses following deprivation of circulating androgens originating from the testis and adrenal glands, indicating the existence of oncometabolites beyond androgens. In this study, mass-spectrometry-based screening of clinical specimens and a retrospective analysis on...
Autores principales: | Hou, Zemin, Huang, Shengsong, Mei, Zejie, Chen, Longlong, Guo, Jiacheng, Gao, Yuanyuan, Zhuang, Qian, Zhang, Xuebin, Tan, Qilong, Yang, Tao, Liu, Ying, Chi, Yongnan, Qi, Lifengrong, Jiang, Ting, Shao, Xuefeng, Wu, Yan, Xu, Xiaojun, Qin, Jun, Ren, Ruobing, Tang, Huiru, Wu, Denglong, Li, Zhenfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040187/ https://www.ncbi.nlm.nih.gov/pubmed/35492874 http://dx.doi.org/10.1016/j.xcrm.2022.100561 |
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