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Accurate and highly interpretable prediction of gene expression from histone modifications

BACKGROUND: Histone Mark Modifications (HMs) are crucial actors in gene regulation, as they actively remodel chromatin to modulate transcriptional activity: aberrant combinatorial patterns of HMs have been connected with several diseases, including cancer. HMs are, however, reversible modifications:...

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Detalles Bibliográficos
Autores principales: Frasca, Fabrizio, Matteucci, Matteo, Leone, Michele, Morelli, Marco J., Masseroli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040271/
https://www.ncbi.nlm.nih.gov/pubmed/35473556
http://dx.doi.org/10.1186/s12859-022-04687-x