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Variance of allele balance calculated from low coverage sequencing data infers departure from a diploid state
BACKGROUND: Polyploidy and heterokaryosis are common and consequential genetic phenomena that increase the number of haplotypes in an organism and complicate whole-genome sequence analysis. Allele balance has been used to infer polyploidy and heterokaryosis in diverse organisms using read sets seque...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040317/ https://www.ncbi.nlm.nih.gov/pubmed/35468720 http://dx.doi.org/10.1186/s12859-022-04685-z |