Cargando…

SARS-CoV-2 pan-variant inhibitory peptides deter S1-ACE2 interaction and neutralize delta and omicron pseudoviruses

Approved neutralizing antibodies that target the prototype Spike are losing their potency against the emerging variants of concern (VOCs) of SARS-CoV-2, particularly Omicron. Although SARS-CoV-2 is continuously adapting the host environment, emerging variants recognize the same ACE2 receptor for cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Masaud, Ung Moon, Sung, Hyun Kim, Jang, Thanh Thao, Trinh, Goo Woo, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040525/
https://www.ncbi.nlm.nih.gov/pubmed/35495107
http://dx.doi.org/10.1016/j.csbj.2022.04.030