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Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship

tRNAs purified from non-pathogenic Escherichia coli strains (NPECSs) possess cytotoxic properties on colorectal cancer cells. In the present study, the bioactivity of tRNA halves and tRNA fragments (tRFs) derived from NPECSs are investigated for their anticancer potential. Both the tRNA halves and t...

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Detalles Bibliográficos
Autores principales: Cao, Kai-Yue, Pan, Yu, Yan, Tong-Meng, Tao, Peng, Xiao, Yi, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040620/
https://www.ncbi.nlm.nih.gov/pubmed/35400173
http://dx.doi.org/10.1128/msystems.00164-22