Biosensor-Coupled In Vivo Mutagenesis and Omics Analysis Reveals Reduced Lysine and Arginine Synthesis To Improve Malonyl-Coenzyme A Flux in Saccharomyces cerevisiae

Malonyl-coenzyme A (malonyl-CoA) is an important precursor for producing various chemicals, but its low availability limits the synthesis of downstream products in Saccharomyces cerevisiae. Owing to the complexity of metabolism, evolutionary engineering is required for developing strains with improv...

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Detalles Bibliográficos
Autores principales: Qiu, Chenxi, Huang, Mingtao, Hou, Yishan, Tao, Huilin, Zhao, Jianzhi, Shen, Yu, Bao, Xiaoming, Qi, Qingsheng, Hou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040634/
https://www.ncbi.nlm.nih.gov/pubmed/35229648
http://dx.doi.org/10.1128/msystems.01366-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040634/
https://www.ncbi.nlm.nih.gov/pubmed/35229648
http://dx.doi.org/10.1128/msystems.01366-21

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