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New pyridine and chromene scaffolds as potent vasorelaxant and anticancer agents

Based on studies that have reported the association between cancer and cardiovascular diseases, new series of pyridine- (3a–o) and/or chromene- (4a–e) carbonitrile analogous were designed, synthesized and screened for their vasodilation and cytotoxic properties. The majority of the new chemical enti...

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Detalles Bibliográficos
Autores principales: Dawood, Dina H., Srour, Aladdin M., Saleh, Dalia O., Huff, Kelley J., Greco, Francesca, Osborn, Helen M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040659/
https://www.ncbi.nlm.nih.gov/pubmed/35479558
http://dx.doi.org/10.1039/d1ra04758b