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Role of mTOR through Autophagy in Esophageal Cancer Stemness

SIMPLE SUMMARY: Esophageal cancer (EC) is a highly aggressive disease with a poor prognosis, which seems related to esophageal cancer stem-like cells (CSCs), which reside in a hypoxic niche. We demonstrated, using EC cell lines and patient-derived organoids, that the hypoxia-responding mammalian tar...

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Detalles Bibliográficos
Autores principales: Du, Liang, Wang, Da, Nagle, Peter W., Groen, Andries A. H., Zhang, Hao, Muijs, Christina T., Plukker, John Th. M., Coppes, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040713/
https://www.ncbi.nlm.nih.gov/pubmed/35406578
http://dx.doi.org/10.3390/cancers14071806