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Role of mTOR through Autophagy in Esophageal Cancer Stemness
SIMPLE SUMMARY: Esophageal cancer (EC) is a highly aggressive disease with a poor prognosis, which seems related to esophageal cancer stem-like cells (CSCs), which reside in a hypoxic niche. We demonstrated, using EC cell lines and patient-derived organoids, that the hypoxia-responding mammalian tar...
Autores principales: | Du, Liang, Wang, Da, Nagle, Peter W., Groen, Andries A. H., Zhang, Hao, Muijs, Christina T., Plukker, John Th. M., Coppes, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040713/ https://www.ncbi.nlm.nih.gov/pubmed/35406578 http://dx.doi.org/10.3390/cancers14071806 |
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