Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors

The present study aims to discover novel derivatives as antiapoptotic agents and their protective effects against renal ischemia/reperfusion. Therefore, a series of new thiadiazole analogues 2a–g was designed and synthesized through cyclization of the corresponding opened hydrazinecarbothioamides 1a...

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Detalles Bibliográficos
Autores principales: Mostafa, Sara M., Aly, Ashraf A., Bräse, Stefan, Nieger, Martin, Abdelhafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Abdelhafez, El-Shimaa M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040718/
https://www.ncbi.nlm.nih.gov/pubmed/35408692
http://dx.doi.org/10.3390/molecules27072266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040718/
https://www.ncbi.nlm.nih.gov/pubmed/35408692
http://dx.doi.org/10.3390/molecules27072266

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