Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape

At the time of this writing, December 2021, potential emergence of vaccine escape variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a grave global concern. The interface between the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein and the host receptor (ACE2) o...

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Detalles Bibliográficos
Autores principales: Rochman, Nash D., Faure, Guilhem, Wolf, Yuri I., Freddolino, Peter L., Zhang, Feng, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040817/
https://www.ncbi.nlm.nih.gov/pubmed/35289643
http://dx.doi.org/10.1128/mbio.00135-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040817/
https://www.ncbi.nlm.nih.gov/pubmed/35289643
http://dx.doi.org/10.1128/mbio.00135-22

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