Nontoxigenic Vibrio cholerae Challenge Strains for Evaluating Vaccine Efficacy and Inferring Mechanisms of Protection

Human challenge studies are instrumental for testing cholera vaccines, but these studies use outdated strains and require inpatient facilities. Here, we created next-generation isogenic Ogawa and Inaba O1 V. cholerae challenge strains (ZChol strains) derived from a contemporary Zambian clinical isol...

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Detalles Bibliográficos
Autores principales: Fakoya, Bolutife, Hullahalli, Karthik, Rubin, Daniel H. F., Leitner, Deborah R., Chilengi, Roma, Sack, David A., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040834/
https://www.ncbi.nlm.nih.gov/pubmed/35389261
http://dx.doi.org/10.1128/mbio.00539-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040834/
https://www.ncbi.nlm.nih.gov/pubmed/35389261
http://dx.doi.org/10.1128/mbio.00539-22

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