Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

Defective interfering particles (DIs) contain a considerably smaller genome than the parental virus but retain replication competency. As DIs can directly or indirectly alter propagation kinetics of the parental virus, they offer a novel approach to antiviral therapy, capitalizing on knowledge from...

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Detalles Bibliográficos
Autores principales: Welch, Stephen R., Spengler, Jessica R., Harmon, Jessica R., Coleman-McCray, JoAnn D., Scholte, Florine E. M., Genzer, Sarah C., Lo, Michael K., Montgomery, Joel M., Nichol, Stuart T., Spiropoulou, Christina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040845/
https://www.ncbi.nlm.nih.gov/pubmed/35297677
http://dx.doi.org/10.1128/mbio.03294-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040845/
https://www.ncbi.nlm.nih.gov/pubmed/35297677
http://dx.doi.org/10.1128/mbio.03294-21

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