High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response

Suppression of the host innate immune response is a critical aspect of viral replication. Upon infection, viruses may introduce one or more proteins that inhibit key immune pathways, such as the type I interferon pathway. However, the ability to predict and evaluate viral protein bioactivity on targ...

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Detalles Bibliográficos
Autores principales: Ng, Tai L., Olson, Erika J., Yoo, Tae Yeon, Weiss, H. Sloane, Koide, Yukiye, Koch, Peter D., Rollins, Nathan J., Mach, Pia, Meisinger, Tobias, Bricken, Trenton, Chang, Timothy Z., Molloy, Colin, Zürcher, Jérôme, Chang, Roger L., Mitchison, Timothy J., Glass, John I., Marks, Debora S., Way, Jeffrey C., Silver, Pamela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040872/
https://www.ncbi.nlm.nih.gov/pubmed/35319251
http://dx.doi.org/10.1128/msystems.01466-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040872/
https://www.ncbi.nlm.nih.gov/pubmed/35319251
http://dx.doi.org/10.1128/msystems.01466-21

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