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ZnCl(2)-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones

A ZnCl(2)-promoted synthesis of 1,3-benzoxazin-4-one from 2-hydroxybenzonitriles and ketones was developed. This method displays facile access to a diverse range of substituted 1,3-benzoxazin-4-ones in good yields. This synthetic protocol has advantages: (i) easy availability of starting material; (...

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Detalles Bibliográficos
Autores principales: Su, Ziqi, Chai, Hongxin, Xu, Juan, Li, Jiarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040917/
https://www.ncbi.nlm.nih.gov/pubmed/35480257
http://dx.doi.org/10.1039/d1ra04194k