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Cobalt catalysed aminocarbonylation of thiols in batch and flow for the preparation of amides

The synthesis of amides from thiols through a cobalt-catalyzed aminocarbonylation is shown. After optimizing all the reaction parameters, the methodology makes possible the obtention of amides with variable yields, while competing reactions such as the formation of disulfides and ureas can be limite...

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Detalles Bibliográficos
Autores principales: Orduña, Jose Maria, Domínguez, Gema, Pérez-Castells, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041104/
https://www.ncbi.nlm.nih.gov/pubmed/35480268
http://dx.doi.org/10.1039/d1ra04736a