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Synthesis and biological evaluation of PET tracers designed for imaging of calcium activated potassium channel 3.1 (K(Ca)3.1) channels in vivo

Expression of the Ca(2+) activated potassium channel 3.1 (K(Ca)3.1) channel (also known as the Gàrdos channel) is dysregulated in many tumor entities and has predictive power with respect to patient survival. Therefore, a positron emission tomography (PET) tracer targeting this ion channel could ser...

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Detalles Bibliográficos
Autores principales: Brömmel, Kathrin, Konken, Christian Paul, Börgel, Frederik, Obeng-Darko, Henry, Schelhaas, Sonja, Bulk, Etmar, Budde, Thomas, Schwab, Albrecht, Schäfers, Michael, Wünsch, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041111/
https://www.ncbi.nlm.nih.gov/pubmed/35480282
http://dx.doi.org/10.1039/d1ra03850h