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Synthesis of spirocyclic Δ(4)-isoxazolines via [3 + 2] cycloaddition of indanone-derived ketonitrones with alkynes
A [3 + 2] cycloaddition of indanone-derived nitrones and alkynes under mild conditions is developed, allowing facile synthesis of spirocyclicindenyl isoxazolines with structural diversity. The sequential protocol of generated in situ ketonitrone from unsaturated ketones and N-alkylhydroxylamines is...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041119/ https://www.ncbi.nlm.nih.gov/pubmed/35480251 http://dx.doi.org/10.1039/d1ra06063e |