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Synthesis of spirocyclic Δ(4)-isoxazolines via [3 + 2] cycloaddition of indanone-derived ketonitrones with alkynes

A [3 + 2] cycloaddition of indanone-derived nitrones and alkynes under mild conditions is developed, allowing facile synthesis of spirocyclicindenyl isoxazolines with structural diversity. The sequential protocol of generated in situ ketonitrone from unsaturated ketones and N-alkylhydroxylamines is...

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Detalles Bibliográficos
Autores principales:	Liu, Yilin, Liu, Jiaxue, Liu, Yan-Yun, Tang, Boxiao, Lin, Hongwei, Li, Yuanxiang, Zhang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041119/ https://www.ncbi.nlm.nih.gov/pubmed/35480251 http://dx.doi.org/10.1039/d1ra06063e

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