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Validation of an insertion-engineered isoprene synthase as a strategy to functionalize terpene synthases

Terpene synthases are biotechnologically-relevant enzymes with a variety of applications. However, they are typically poor catalysts and have been difficult to engineer. Structurally, most terpene synthases share two conserved domains (α- and β-domains). Some also contain a third domain containing a...

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Detalles Bibliográficos
Autores principales: Gonzalez-Esquer, C. Raul, Ferlez, Bryan, Weraduwage, Sarathi M., Kirst, Henning, Lantz, Alexandra T., Turmo, Aiko, Sharkey, Thomas D., Kerfeld, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041124/
https://www.ncbi.nlm.nih.gov/pubmed/35480253
http://dx.doi.org/10.1039/d1ra05710c