Bis-indolylation of aldehydes and ketones using silica-supported FeCl(3): molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding sites

We report herein an operationally simple, efficient and versatile procedure for the synthesis of bis-indolylmethanes via the reaction of indoles with aldehydes or ketones in the presence of silica-supported ferric chloride under grindstone conditions. The prepared supported catalyst was characterize...

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Detalles Bibliográficos
Autores principales: Deb, Barnali, Debnath, Sudhan, Chakraborty, Ankita, Majumdar, Swapan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041420/
https://www.ncbi.nlm.nih.gov/pubmed/35498942
http://dx.doi.org/10.1039/d1ra05679d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041420/
https://www.ncbi.nlm.nih.gov/pubmed/35498942
http://dx.doi.org/10.1039/d1ra05679d

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