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Bis-indolylation of aldehydes and ketones using silica-supported FeCl(3): molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding sites

We report herein an operationally simple, efficient and versatile procedure for the synthesis of bis-indolylmethanes via the reaction of indoles with aldehydes or ketones in the presence of silica-supported ferric chloride under grindstone conditions. The prepared supported catalyst was characterize...

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Detalles Bibliográficos
Autores principales:	Deb, Barnali, Debnath, Sudhan, Chakraborty, Ankita, Majumdar, Swapan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041420/ https://www.ncbi.nlm.nih.gov/pubmed/35498942 http://dx.doi.org/10.1039/d1ra05679d

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