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Synthesis, cytotoxicity evaluation and molecular docking studies on 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone derivatives

2′,4′-Dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (DMC, 1) was isolated from seeds of Syzygium nervosum A.Cunn. ex DC. exhibiting intriguing biological activities. Herein, thirty three DMC derivatives including 4′-O-monosubstituted-DMC (2), 7-O-acylated-4-hydroxycoumarin derivatives (3), stilbene–co...

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Detalles Bibliográficos
Autores principales: Khamto, Nopawit, Chaichuang, Lada, Rithchumpon, Puracheth, Phupong, Worrapong, Bhoopong, Phuangthip, Tateing, Suriya, Pompimon, Wilart, Semakul, Natthawat, Chomsri, Ni-orn, Meepowpan, Puttinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041536/
https://www.ncbi.nlm.nih.gov/pubmed/35496846
http://dx.doi.org/10.1039/d1ra05445g