The Challenges of Predicting Drug-Induced QTc Prolongation in Humans

The content of this article derives from a Health and Environmental Sciences Institute (HESI) consortium with a focus to improve cardiac safety during drug development. A detailed literature review was conducted to evaluate the concordance between nonclinical repolarization assays and the clinical t...

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Detalles Bibliográficos
Autores principales: Valentin, Jean-Pierre, Hoffmann, Peter, Ortemann-Renon, Catherine, Koerner, John, Pierson, Jennifer, Gintant, Gary, Willard, James, Garnett, Christine, Skinner, Matthew, Vargas, Hugo M, Wisialowski, Todd, Pugsley, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
In-Depth Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041548/
https://www.ncbi.nlm.nih.gov/pubmed/35148401
http://dx.doi.org/10.1093/toxsci/kfac013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041548/
https://www.ncbi.nlm.nih.gov/pubmed/35148401
http://dx.doi.org/10.1093/toxsci/kfac013

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