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The Challenges of Predicting Drug-Induced QTc Prolongation in Humans

The content of this article derives from a Health and Environmental Sciences Institute (HESI) consortium with a focus to improve cardiac safety during drug development. A detailed literature review was conducted to evaluate the concordance between nonclinical repolarization assays and the clinical t...

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Detalles Bibliográficos
Autores principales:	Valentin, Jean-Pierre, Hoffmann, Peter, Ortemann-Renon, Catherine, Koerner, John, Pierson, Jennifer, Gintant, Gary, Willard, James, Garnett, Christine, Skinner, Matthew, Vargas, Hugo M, Wisialowski, Todd, Pugsley, Michael K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	In-Depth Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041548/ https://www.ncbi.nlm.nih.gov/pubmed/35148401 http://dx.doi.org/10.1093/toxsci/kfac013

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