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Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells
Small molecule fluorescent probes provide a powerful labelling technology to enhance our understanding of particular proteins. However, the discovery of a proper fluorescent probe for detecting PDE5 is still a challenge due to the highly conservative structure of the catalytic domain in the phosphod...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041563/ https://www.ncbi.nlm.nih.gov/pubmed/35495504 http://dx.doi.org/10.1039/d1ra06247f |