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Discovery of catalytic-site-fluorescent probes for tracing phosphodiesterase 5 in living cells

Small molecule fluorescent probes provide a powerful labelling technology to enhance our understanding of particular proteins. However, the discovery of a proper fluorescent probe for detecting PDE5 is still a challenge due to the highly conservative structure of the catalytic domain in the phosphod...

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Detalles Bibliográficos
Autores principales: Qiu, Meiying, Wu, Deyan, Huang, Yi-You, Huang, Yue, Zhou, Qian, Tian, Yijing, Guo, Lei, Gao, Yuqi, Luo, Hai-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041563/
https://www.ncbi.nlm.nih.gov/pubmed/35495504
http://dx.doi.org/10.1039/d1ra06247f