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Development of stealth liposomal formulation of celecoxib: In vitro and in vivo evaluation

Celecoxib (CLB) is a highly hydrophobic selective cyclo-oxygenase inhibitor with high plasma protein binding and undergoes extensive hepatic metabolism. CLB is highly effective in the treatment of osteo and rheumatoid arthritis as first line therapy but produces severe gastro-intestinal toxicities a...

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Detalles Bibliográficos
Autores principales: Begum, M. Yasmin, M. Osmani, Riyaz Ali, Alqahtani, Ali, Ghazwani, Mohammed, Hani, Umme, Ather, Hissana, Atiya, Akhtar, Rahamathulla, Mohamed, Siddiqua, Ayesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041753/
https://www.ncbi.nlm.nih.gov/pubmed/35472207
http://dx.doi.org/10.1371/journal.pone.0264518