Ubiquitin ligase activity inhibits Cdk5 to control axon termination

The Cdk5 kinase plays prominent roles in nervous system development, plasticity, behavior and disease. It also has important, non-neuronal functions in cancer, the immune system and insulin secretion. At present, we do not fully understand negative regulatory mechanisms that restrict Cdk5. Here, we...

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Detalles Bibliográficos
Autores principales: Desbois, Muriel, Opperman, Karla J., Amezquita, Jonathan, Gaglio, Gabriel, Crawley, Oliver, Grill, Brock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041834/
https://www.ncbi.nlm.nih.gov/pubmed/35421092
http://dx.doi.org/10.1371/journal.pgen.1010152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041834/
https://www.ncbi.nlm.nih.gov/pubmed/35421092
http://dx.doi.org/10.1371/journal.pgen.1010152

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