Multi-targeting of K-Ras domains and mutations by peptide and small molecule inhibitors

K-Ras activating mutations are significantly associated with tumor progression and aggressive metastatic behavior in various human cancers including pancreatic cancer. So far, despite a large number of concerted efforts, targeting of mutant-type K-Ras has not been successful. In this regard, we aime...

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Detalles Bibliográficos
Autores principales: Poorebrahim, Mansour, Abazari, Mohammad Foad, Moradi, Leila, Shahbazi, Behzad, Mahmoudi, Reza, Kalhor, Hourieh, Askari, Hassan, Teimoori-Toolabi, Ladan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041843/
https://www.ncbi.nlm.nih.gov/pubmed/35472201
http://dx.doi.org/10.1371/journal.pcbi.1009962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041843/
https://www.ncbi.nlm.nih.gov/pubmed/35472201
http://dx.doi.org/10.1371/journal.pcbi.1009962

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