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Protein import in mitochondria biogenesis: guided by targeting signals and sustained by dedicated chaperones

Mitochondria have a central role in cellular metabolism; they are responsible for the biosynthesis of amino acids, lipids, iron–sulphur clusters and regulate apoptosis. About 99% of mitochondrial proteins are encoded by nuclear genes, so the biogenesis of mitochondria heavily depends on protein impo...

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Detalles Bibliográficos
Autores principales: Dimogkioka, Anna-Roza, Lees, Jamie, Lacko, Erik, Tokatlidis, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041937/
https://www.ncbi.nlm.nih.gov/pubmed/35495482
http://dx.doi.org/10.1039/d1ra04497d