Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells

Cortico-striatal projections are critical components of forebrain circuitry that regulate motivated behaviors. To enable the study of the human cortico-striatal pathway and how its dysfunction leads to neuropsychiatric disease, we developed a method to convert human pluripotent stem cells into regio...

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Detalles Bibliográficos
Autores principales: Miura, Yuki, Li, Min-Yin, Birey, Fikri, Ikeda, Kazuya, Revah, Omer, Thete, Mayuri Vijay, Park, Jin-Young, Puno, Alyssa, Lee, Samuel H., Porteus, Matthew H., Pașca, Sergiu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042317/
https://www.ncbi.nlm.nih.gov/pubmed/33273741
http://dx.doi.org/10.1038/s41587-020-00763-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042317/
https://www.ncbi.nlm.nih.gov/pubmed/33273741
http://dx.doi.org/10.1038/s41587-020-00763-w

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