Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages

Human Interferon (IFN) lambda 3 (IFN-λ3) and IFN-λ4 are closely linked at the IFNL locus and show association with several diseases in genetic studies. Since they are only ~30% identical to each other, to better understand their roles in disease phenotypes, comparative studies are needed. Monocytes...

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Detalles Bibliográficos
Autores principales: De, Manjarika, Bhushan, Anand, Grubbe, William S., Roy, Subhajit, Mendoza, Juan L., Chinnaswamy, Sreedhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042695/
https://www.ncbi.nlm.nih.gov/pubmed/35115664
http://dx.doi.org/10.1038/s41435-022-00164-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042695/
https://www.ncbi.nlm.nih.gov/pubmed/35115664
http://dx.doi.org/10.1038/s41435-022-00164-w

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