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Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages
Human Interferon (IFN) lambda 3 (IFN-λ3) and IFN-λ4 are closely linked at the IFNL locus and show association with several diseases in genetic studies. Since they are only ~30% identical to each other, to better understand their roles in disease phenotypes, comparative studies are needed. Monocytes...
Autores principales: | De, Manjarika, Bhushan, Anand, Grubbe, William S., Roy, Subhajit, Mendoza, Juan L., Chinnaswamy, Sreedhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042695/ https://www.ncbi.nlm.nih.gov/pubmed/35115664 http://dx.doi.org/10.1038/s41435-022-00164-w |
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